Reorganization of the chick basilar papilla after acoustic trauma
نویسندگان
چکیده
منابع مشابه
Reorganization of the chick basilar papilla after acoustic trauma.
The auditory epithelium in birds and mammals consists of a postmitotic population of hair cells and supporting cells. Unlike mammals, birds can regenerate their auditory epithelia after trauma. Recent evidence indicates that supporting cells undergo mitosis after acoustic trauma, suggesting that supporting cells may transdifferentiate into hair cells. The goals of this study were to 1) characte...
متن کاملRelationship between hair cell loss on the chick basilar papilla and threshold shift after acoustic overstimulation.
Three groups of chickens were continuously exposed to 125dB SPL pure tones at either 500, 1500 or 3000 Hz for 12 h. Ten days after the exposure to noise, a good correlation was found between the percentage of hair cell loss and the threshold shifts of the eighth nerve action potential. The data suggest possible roles for the two types’ of hair cells present on the basilar papilla. In addition i...
متن کاملExpression of novel potassium channels in the chick basilar papilla.
Ionic currents are critical for the functioning of the inner ear auditory sensory epithelium. We set out to identify and molecularly clone the genes encoding the channels responsible for several currents in the chick basilar papilla. Here we describe an inward-rectifying K+ channel, cKir2.3, present in both hair cells and support cells in the apical end of the chick basilar papilla. The biophys...
متن کاملDevelopmental assembly of transduction apparatus in chick basilar papilla.
Hair cells, the sensory receptors of auditory and vestibular systems, use a transducer apparatus that renders them remarkably sensitive to mechanical displacement as minute as 1 nm. To study the embryonic development of the transducer apparatus in hair cells of the chick auditory papilla, we examined hair cells that have been labeled with N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl) ...
متن کاملElectron microscopy of degenerative changes in the chick basilar papilla after gentamicin exposure.
We present a sequential study of the substructural alterations in the chick basilar papilla at the earliest signs of hair cell degeneration. Three-day posthatch chicks received a single injection of gentamicin (300 mg/kg) and were killed at 6, 8, 12, 15, 18, 21, and 24 hours after the injection. The basilar papillae were studied by conventional transmission electron microscopy. Examination was ...
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ژورنال
عنوان ژورنال: The Journal of Comparative Neurology
سال: 1993
ISSN: 0021-9967,1096-9861
DOI: 10.1002/cne.903300408